Functional tissue models are gaining importance in drug development, toxicology, and regenerative medicine. Cryopreservation, however, remains labor-intensive, error-prone, and difficult to scale. The Fraunhofer Institute for Material and Beam Technology IWS, together with other Fraunhofer institutes, has developed an automated platform that standardizes vitrification and delivers reproducible results. The “COLDIMPACT” project, part of the Fraunhofer preliminary research program Prepare, creates industry-oriented processes that replace manual, case-by-case work and pave the way for transfer into application and production.