Fraunhofer Institute for Material and Beam Technology IWSPrecise control and regulation of microfluidic systems are essential for the reproducible execution of biological experiments. This requires high-resolution measurement of flow rates, pressures, temperatures, and chemical parameters. Based on these measurements, the development of appropriate control strategies and associated devices enables the reliable implementation of complex processes such as perfusion, gradient generation, mass transport, and dynamic stimulation.
Systematic Research
MPScontrol Precisely Controls Flow in Organ-on-chip Systems
© Fraunhofer IWS
Control Concepts for Micro and Bio Applications
Modular MPS control unit platforms for customer-specific applications.
Expertise and Methods
Fluidic Control and Regulation Systems
- Control of microfluidic pumps and valves
- Pressure and flow regulation
- Dynamic perfusion programs
- Gradient and pulse control for biological stimuli
Sensor Integration and Signal Processing
- Integration of O₂, CO₂, pH, and temperature sensors
- Optical sensing and imaging-based feedback
- Electronic data acquisition (DAQ) and signal monitoring
- Calibration and control algorithms for real-time operation
Hardware and Software Development
- Embedded systems (microcontrollers, FPGA, SoC)
- User interfaces and control software
- Automated workflows and sequence control
- Integration into laboratory automation systems
Modular Platforms for Bioapplications
- Control solutions for organ-on-chip and multi-organ models
- Customizable fluidic modules for different chip systems
- Control of biologically relevant environmental parameters
- Compatibility with imaging systems, analytical instruments, and sensor platforms
Video: Microfluidic Organ-on-chip System
Microfluidic organ-on-chip system with circulating perfusion and integrated sensor technology for precise monitoring and control of culture parameters.